原创力文档destabilizing protein polymorphisms in the genetic background direct phenotypic expression of mutant sod1 toxicity不稳定蛋白多态性的遗传背景直接sod1基因突变的表型表达毒性.pdfVIP
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destabilizing protein polymorphisms in the genetic background direct phenotypic expression of mutant sod1 toxicity不稳定蛋白多态性的遗传背景直接sod1基因突变的表型表达毒性
Destabilizing Protein Polymorphisms in the Genetic
Background Direct Phenotypic Expression of Mutant
SOD1 Toxicity
¤
Tali Gidalevitz, Thomas Krupinski, Susana Garcia , Richard I. Morimoto*
Department of Biochemistry, Molecular Biology, and Cell Biology, Rice Institute for Biomedical Research, Northwestern University, Evanston, Illinois, United States of
America
Abstract
Genetic background exerts a strong modulatory effect on the toxicity of aggregation-prone proteins
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