cysteinyl-trna deacylation can be uncoupled from protein synthesiscysteinyl-trna脱酰作用可以从蛋白质合成非耦合.pdfVIP

Cysteinyl-tRNA Deacylation Can Be Uncoupled from Protein Synthesis Alexandre David, Suman R. Das, James S. Gibbs, Jack R. Bennink, Jonathan W. Yewdell* Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, United States of America Abstract Aminoacyl-tRNA synthetases (ARSs) are critical components of protein translation, providing ribosomes with aminoacyl- tRNAs. In return, ribosomes release uncharged tRNAs as ARS substrates. Here, we show that tRNA deacylation can be uncoupled from prote