detecting coevolution in and among protein domains检测蛋白质之间的共同进化的领域.pdfVIP

Detecting Coevolution in and among Protein Domains 1* 2 Chen-Hsiang Yeang , David Haussler 1 Simons Center for Systems Biology, Institute for Advanced Study, Princeton, New Jersey, United States of America, 2 Center for Biomolecular Science and Engineering, University of California Santa Cruz, Santa Cruz, California, United States of America Correlated changes of nucleic or amino acids have provided strong information about the structures and interactions of molecules. Despite the rich literature in coevolutionary sequence analysis,