determinants of disease presentation and outcome during cryptococcosis the cryptoad study的决定因素在隐球菌cryptoad研究疾病表现和结果.pdfVIP
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determinants of disease presentation and outcome during cryptococcosis the cryptoad study的决定因素在隐球菌cryptoad研究疾病表现和结果
PLoS MEDICINE
Determinants of Disease Presentation and
Outcome during Cryptococcosis:
The CryptoA/D Study
1* ´ 2 3 1,4
Franc¸oise Dromer , Simone Mathoulin-Pelissier , Odile Launay , Olivier Lortholary , the French Cryptococcosis Study
Group
´ ´ ´ ´ ´
1 Unite de Mycologie Moleculaire, Centre National de Reference Mycologie et Antifongiques, CNRS URA3042, Institut Pasteur, Paris, France, 2 Institut Bergonie, Centre
´ ´ ˆ ´
Regional de Lutte Contre le Cancer du Sud-Ouest, Bordeaux, France, 3 Universite Paris V, Hopital Cochin, Service de Medecine Interne, CIC Vaccinologie Cochin–Pasteur,
´ ˆ
Paris, France, 4 Universite Paris V–Hopital Necker-Enfants Malades, Service des Maladies Infectieuses et Tropicales, Centre d’Infectiologie Necker-Pasteur, Paris, France
Funding: The financial supports of A B S T R A C T
Ensemble Contre le SIDA
(SIDACTION) and of the Institut
Pasteur, Programme de Recherche
Clinique to F. Dromer are gratefully Background
acknowledged. The funders had no
role in study design, data collection Cryptococcosis is a life-threatening opportunistic fungal infection in both HIV-positive
and analysis, decision to publish, or and -negative patients. Information on clinical presentation and therapeutic guidelines, derived
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