differential gonogo activity in both contingent negative variation and spectral power微分gonogo活动或有消极的变化和光谱的力量.pdfVIP

Differential Go/NoGo Activity in Both Contingent Negative Variation and Spectral Power 1 1,2 3 1,4 5,6 Ingrid Funderud *, Magnus Lindgren , Marianne Løvstad , Tor Endestad , Bradley Voytek , Robert T. Knight6,7, Anne-Kristin Solbakk1 1 Department of Neuropsychiatry and Psychosomatic Medicine, Division of Surgery and Clinical Neuroscience, Oslo University Hospital - Rikshospitalet, Oslo, Norway, 2 Department of Psychology, Lund University, Lund, Sweden, 3 Sunnaas Rehabilitation Hospital, Nesodden, Norway, 4 Department of Psychology, University of Oslo, Oslo, Norway, 5 Department of Neurology, University of California San Francisco, San Francisco, California, United States of America, 6 Helen Wills Neuroscience Institute, University of California, Berkeley, California, United States of America, 7 Department of Psychology, University of California, Berkeley, California, United States of America Abstract We investigated whether both the contingent negative variation (CNV), an event-related potential index of preparatory brain activity, and event-related oscillatory EEG activity differentiated Go and NoGo trials in a delayed response task. CNV and spectral power (4–100 Hz) were calculated from EEG activity in the preparatory interval in 16 healthy adult participants. As previously reported, CNV amplitudes were higher in Go compared to NoGo trials. In addition, event-related spectral power of the Go condition was reduced in the theta to low gamma range compared to the NoGo condition, confirming that preparing to respond is associated with modulation of event-related spectral activity as well as the CNV. Altogether, the impact of the experimental manipulation on bot