discovery and characterization of human exonic transcriptional regulatory elements发现和描述的人类其实转录监管元素.pdfVIP

Discovery and Characterization of Human Exonic Transcriptional Regulatory Elements Arshad H. Khan, Andy Lin, Desmond J. Smith* Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America Abstract We sought exonic transcriptional regulatory elements by shotgun cloning human cDNA fragments into luciferase reporter vectors and measuring the resulting expression levels in liver cells. We uncovered seven regulatory elements within coding regions and three