原创力文档drosophila xpd regulates cdk7 localization, mitotic kinase activity, spindle dynamics, and chromosome segregation果蝇xpd调节cdk7本地化,有丝分裂激酶活性,主轴动力学和染色体分离.pdfVIP
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drosophila xpd regulates cdk7 localization, mitotic kinase activity, spindle dynamics, and chromosome segregation果蝇xpd调节cdk7本地化,有丝分裂激酶活性,主轴动力学和染色体分离
Drosophila Xpd Regulates Cdk7 Localization, Mitotic
Kinase Activity, Spindle Dynamics, and Chromosome
Segregation
Xiaoming Li.¤, Olivier Urwyler., Beat Suter*
Institute of Cell Biology, University of Bern, Bern, Switzerland
Abstract
The trimeric CAK complex functions in cell cycle control by phosphorylating and activating Cdks while TFIIH-linked CAK
functions in transcription. CAK also associates into a tetramer with Xpd, and our analysis of young Drosophila embryos that
do not require transcription now suggests a cell cycle function for this interaction. xpd is e
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