dynamic analysis of integrated signaling, metabolic, and regulatory networks动态分析的集成信号、代谢和监管网络.pdfVIP

Dynamic Analysis of Integrated Signaling, Metabolic, and Regulatory Networks Jong Min Lee.¤a, Erwin P. Gianchandani., James A. Eddy¤b, Jason A. Papin* Department of Biomedical Engineering, University of Virginia Health System, Charlottesville, Virginia, United States of America Abstract Extracellular cues affect signaling, metabolic, and regulatory processes to elicit cellular responses. Although intracellular signaling, metabolic, and regulatory networks are highly integrated, previous analyses have largely focused on independent processes (e.g., meta