diverse effects on mitochondrial and nuclear functions elicited by drugs and genetic knockdowns in bloodstream stage trypanosoma brucei药物引发的不同影响线粒体和核函数和遗传击倒在血液阶段锥虫属brucei.pdfVIP

Diverse Effects on Mitochondrial and Nuclear Functions Elicited by Drugs and Genetic Knockdowns in Bloodstream Stage Trypanosoma brucei Christal Worthen1.¤, Bryan C. Jensen1., Marilyn Parsons 1,2* 1 Seattle Biomedical Research Institute, Seattle, Washington, United States of America, 2 Department of Global Health, University of Washington, Seattle, Washington, United States of America Abstract Background: The options for treating the fatal disease human African trypanosomiasis are limited to a few drugs that are toxic or facing increasing resistance. New drugs th