economic appraisal of ontarios universal influenza immunization program a cost-utility analysis经济评价安大略省的通用流感疫苗接种计划的成本效用分析.pdfVIP

Economic Appraisal of Ontario’s Universal Influenza Immunization Program: A Cost-Utility Analysis 1,2,3 4,5,6 3,7 1,8 9 Beate Sander *, Jeffrey C. Kwong , Chris T. Bauch , Andreas Maetzel , Allison McGeer , Janet M. Raboud6,9, Murray Krahn1,2,3,10,11 1 Department of Health Policy, Management and Evaluation, University of Toronto, Toronto, Canada, 2 Division of Clinical Decision-Making and Health Care Research, University Health Network, Toronto, Canada, 3 Toronto Health Economics and Technology Assessment Collaborative, Toronto, Canada, 4 Institute for Clinical Evaluative Sciences, Toronto, Canada, 5 Department of Family and Community Medicine, University of Toronto, Toronto, Canada, 6 Dalla Lana School of Public Health, University of Toronto, Toronto, Canada, 7 Department of Mathematics and Statistics, University of Guelph, Guelph, Canada, 8 Amgen (Europe) GmbH, Zug, Switzerland, 9 Division of Infectious Diseases, University Health Network, Toronto, Canada, 10 Faculty of Pharmacy, University of Toronto, Toronto, Canada, 11 Department of Medicine, University of Toronto, Toronto, Canada Abstract Background: In July 2000, the province of Ontario, Canada, initiated a universal influenza immunization program (UIIP) to provide free seasonal influenza vaccines for the entire population. This is the first large-scale program of its kind worldwide. The objective of this study was to conduct an economic appraisal of Ontario’s UIIP compared to a targeted influenza immunization program (TIIP). Methods and Findings: A cost-utility analysis using Ontario health administrative data was performed. The study was informed by a companion ecological study comparing physician visits, emergency depart