effects of interferon-αβ on hbv replication determined by viral loadinterferon-αβ对乙肝病毒复制的影响取决于病毒载量.pdfVIP

Effects of Interferon-a/b on HBV Replication Determined by Viral Load Yongjun Tian, Wen-ling Chen, Jing-hsiung James Ou* Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America Abstract Interferons a and b (IFN-a/ b) are type I interferons produced by the host to control microbial infections. However, the use of IFN-a to treat hepatitis B virus (HBV) patients generated sustained response to only a minority of patients. By using