histone h2a mono-ubiquitination is a crucial step to mediate prc1-dependent repression of developmental genes to maintain es cell identity组蛋白h2a mono-ubiquitination调解prc1-dependent镇压是一个关键的一步发展基因保持es细胞的身份.pdfVIP
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histone h2a mono-ubiquitination is a crucial step to mediate prc1-dependent repression of developmental genes to maintain es cell identity组蛋白h2a mono-ubiquitination调解prc1-dependent镇压是一个关键的一步发展基因保持es细胞的身份
Histone H2A Mono-Ubiquitination Is a Crucial Step to
Mediate PRC1-Dependent Repression of Developmental
Genes to Maintain ES Cell Identity
1,2 3. 1. 1 1 4
Mitsuhiro Endoh *, Takaho A. Endo , Tamie Endoh , Kyo-ichi Isono , Jafar Sharif , Osamu Ohara ,
3 5 6 6 7,8
Tetsuro Toyoda , Takashi Ito , Ragnhild Eskeland , Wendy A. Bickmore , Miguel Vidal ,
Bradley E. Bernstein9,10,11, Haruhiko Koseki1,2*
1 Laboratory for Developmental Genetics, RIKEN Research Center for Allergy and Immunology, Yokohama, Japan, 2 Core Research for Evolutional Science and Technology,
Japan Science and Technology Agency, Yokohama, Japan, 3 RIKEN Bioinformatics and System Engineering Division, Yokohama, Japan, 4 Laboratories for
Immunogenomics, RIKEN Research Center for Allergy and Immunology, Yokohama, Japan, 5 Department of Biochemistry, Nagasaki University School of Medicine,
Nagasaki, Japan, 6 MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom, 7 Cell Proliferation and
´
Development, Centro de Investigaciones Biologicas, Consejo Superior de Investigaciones Cientıficas, Madrid, Spain, 8 Research Unit for Immunoepigenetics, RIKEN
Research Center for Allergy and Immunology, Yokohama, Japan, 9 Molecular Pathology Unit and Center for Cancer Research, Massachusetts General Hospital,
Charlestown, Massachusetts, United States of America, 10 Department of Path
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