nucleolar association and transcriptional inhibition through 5s rdna in mammals通过5 s rdna核仁的协会和转录抑制哺乳动物.pdfVIP

Nucleolar Association and Transcriptional Inhibition through 5S rDNA in Mammals Andrew M. Fedoriw, Joshua Starmer, Della Yee, Terry Magnuson* Department of Genetics, Carolina Center for Genome Sciences, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America Abstract Changes in the spatial positioning of genes within the mammalian nucleus have been associated with transcriptional differences and thus have been hypothesized as a mode of regulation. In particular, the localiza