soybeans ameliolate diabetic nephropathy in rats大豆ameliolate在大鼠糖尿病肾病.pdfVIP

Advance Access Publication 20 March 2008 eCAM 2010;7(4)433–440 doi:10.1093/ecam/nen021 Original Article Soybeans Ameliolate Diabetic Nephropathy in Rats 1 2 2 2 3 Young Eun Choi , Soo Kyung Ahn , Won Taek Lee , Jong Eun Lee , Seung Hwa Park , Bang Bu Yoon4 and Kyung Ah Park2 1Department of Family Medicine, Ilsan Medical Insurance Hospital, 2Department of Anatomy Brain Research Institute, Yonsei University College of Medicine, 3Department of Anatomy, Konkuk University College of Medicine and 4Department of Family Medicine, Yonsei University College of Medicine, Seoul, Korea Diabetic nephropathy is one of the most frequent and serious complications of diabetes mellitus. Soybeans have been shown to reduce urinary albumin excretion and total cholesterol in non-diabetic patients with nephrotic syndrome. However, reports focusing specifically on diabetic nephropathy are scarce and the available results are inconsistent. It was reported that soybean consumption reduced urinary protein excretion in type 1 diabetic patients with diabetic nephropathy, whereas it was found to elicit an increase in urinary protein excretion when soybeans were consumed by type 2 diabetic patients. This study aims to investigate the effects of soybean in