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生物工程概论(introduction to bioengineering)
生物工程概论(introduction to bioengineering)
Biological engineering, stem cell, biological engineering, progress
Stem cell (StemCells) is a class of undifferentiated cells or primitive cells. It is a pluripotent cell with the ability to replicate itself. Under certain conditions, stem cells can differentiate into multifunctional cells in the body, forming any kind of tissues and organs, so as to realize the internal construction and self rehabilitation ability of the organism. In this paper, the progress of stem cell bioengineering is briefly introduced:
Classification and origin of stem cells
According to its developmental stage, cells can be divided into embryonic stem cells (EmbryonicStemCell) and adult stem cells (AdultStemCell). Embryonic stem cells including ES cells (EmbryonicStemCell), EG (EmbryonicGermCell) cells; adult stem cells including neural stem cells (NeuralStemCe11, NSC), blood stem cells (HematopoieticStemCell, HSC), bone marrow mesenchymal stem cells (MesenchymalStemCell, MSC), epidermal stem cells (EPidexmisStemCell). It is also reported that stem cells can be divided into three groups according to their differentiation potential: first, totipotent stem cells (TotipotentStemCell) and two embryonic stem cells (EmbryonicStemCell)
Three of them are pluripotent stem cells (MultipotentStemCe11).
It has been reported that embryonic stem cells can originate from teratoma cells (EC), morula cells (ES), blastocysts, cell clusters (ES), embryoid bodies (ES), and reproductive primordium cells (EG).
When the fertilized egg develops into a blastocyst, the inner cell mass (InnerCellMass) were cultured and separated, under certain conditions, these cells in vitro indefinitely proliferation passage, while maintaining its versatility, so called embryonic stem cells. If the embryonic stem cells were cultured, the leukemia inhibitory factor LIF (LeukaemiaInhlbitory) was added
Factor can remain undifferentiated, and if LIF is removed, embryonic stem cells differentiate r
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