第五章 肥胖症（The fifth chapter is obesity）.doc

第五章 肥胖症（The fifth chapter is obesity） The fifth chapter is obesity Obesity (obesity) refers to excessive accumulation of fat in the body and / or abnormal distribution and weight gain. It is a chronic metabolic disease caused by the interaction of many factors, including heredity and environmental factors. Prevalence of overweight and obesity in some developed countries and regions has reached epidemic levels. It is estimated that in western countries, about half of adults are overweight and obese. The rate is also rising rapidly in Chinas obesity, according to nutrition and health status of residents Chinese (2004) in the report, Chinas adult overweight rate was 22.8% and the obesity rate was 7.1%, estimated prevalence were 200 million and about Obesity, as one of the major components of metabolic syndrome, is closely related to many diseases, such as type 2 diabetes mellitus, dyslipidemia, hypertension, coronary heart disease, stroke and some cancers. Obesity and related diseases can damage the physical and mental health of patients, reduce the quality of life and shorten the life expectancy. It has become one of the most important health problems in the world. The Department of disease control of the Ministry of health of China formulated the guidelines for the prevention and control of overweight and obesity in adults in 2003 (trial). Obesity can be one of the clinical manifestations of some diseases. It is called secondary obesity, accounting for about 1% of obesity. [etiology and pathogenesis] (1) energy balance and weight regulation In vivo there is a fine monitoring and regulatory system to maintain body weight stability, referred to as set-point. Due to the presence of weight adjustment sites, short-term weight gain or loss is automatically compensated and weight tends to revert to the setpoint level. Weight is regulated by both the nervous and endocrine systems and ultimately acts on the effector organs of energy intake and consumption. The cent