联苯双酯（Biphenyl diester）.doc

联苯双酯（Biphenyl diester） Biphenyl diester medical aircraft Biphenyl diester is a common drug for the treatment of viral hepatitis and drug-induced liver injury causing elevated transaminase. In the past, it has the pharmacological action of protecting liver cells and increasing the detoxification function of liver. In particular, the effect of enzyme reduction is obvious, and the toxicity is low and the side effects are small. Catalog Essential information purpose clinical application Character usage and dosage Indication Therapeutic effect Open Essential information purpose clinical application Character usage and dosage Indication Therapeutic effect Open Essential information Molecular formula: C20H18O10 Structural formula Molecular weight: 418.36 Biphenyl diester; 4,4- two methoxy -5,6,5, 6- two times a two oxygen -2,2- two formic acid methyl ester biphenyl English Name: Bifendatatum; Biphenyldicarboxylate purpose Usage: anti hepatitis medicine, used for chronic persistent hepatitis, chronic active hepatitis: fatty liver and other diseases. Bifendate (biphenyldicarboxylate) is an enzyme reducing drug developed in China. It is an intermediate of the synthesis of schisandrin C. Pharmacological experiment: mice after oral administration can reduce caused by CCl4 serum alanine aminotransferase (ALT) increased; experiments also show that can enhance liver detoxification function, reduce the pathological damage of the liver and promote liver regeneration and protect liver cells, improve liver function. clinical application By comparing the clinical self control and the control group, it can obviously reduce the enzyme action. After 1 months, the ALT decreased greatly, more than 80% of the chronic hepatitis was effective, and the effect of degrading enzyme increased with the prolongation of the treatment course. Doses of 15mg, 3/ days oral, 1 months after the drug is still no downward trend, may increase the dose, until 30mg. The effect of enzyme reduction is better in pa