肝癌患者周围血白蛋白mrna检测（Detection of peripheral blood albumin mRNA in patients with liver cancer）.docVIP

肝癌患者周围血白蛋白mrna检测（Detection of peripheral blood albumin mRNA in patients with liver cancer） Detection of peripheral blood albumin mRNA in patients with liver cancer 2011-04-03, Detection, of, albumin, mRNA, in, the, peripheral, blood,, from, patients, with Hepatocellular carcinoma Huang Zhiming, Yuan Shizhen, Zhu Zhaohua, Huang Zhiming Huang, Zhiming, Yuan, Shizhen, Zhu, Zhaohua, et, Al Abstract: Objective hepatocellular carcinoma (HCC) has poor prognosis, and only surgical resection is performed before HCC metastasis It is very difficult to find very small amounts of HCC cells in the blood by morphological methods The. To better identify HCC cells in peripheral blood. Methods reverse transcription polymerase chain reaction (RT-PCR) was used Methods the peripheral blood albumin (mRNA) of 21 patients with HCC and 22 controls was detected. Late results were found The positive rate of HCC patients is high, and it is related to the clinical stage. The positive rate of the patients with pulmonary or portal vein involvement is higher than that without liver Patients with metastatic high (P=0.0032) serum alpha fetoprotein (AFP) 200 g/L and 200 g/L HCC patients There was no significant difference between the positive rates (P 0.05). Conclusion this method is predictive of early micrometastasis in HCC It may play a role in the evaluation of the prognosis of patients with HCC, especially for serum AFP negative or low value HCC The patient is eligible for additional diagnosis. [Keywords] carcinoma, hepatocyte, RNA, Messenger Detection, of, albumin, mRNA, in, the, peripheral, blood, from, patients,, with, hepatocellular, carcinoma Huang, Zhiming*, Yuan, Shizhen, Zhu, Zhaohua, et, al., *Department, of, Gastroenterology, The, First, Affiliated Hospital, of, Wenzhou, Medical, College, Wenzhou 325000 [Abstract] Objective, The, prognosis, of, hepatocellular, carcinoma (HCC), is, poor., The, early Resection, of, tumor, before, micrometastasis, an, important, plays, role, in, the,,