肿瘤标志物检测与临床（Detection and clinical study of tumor markers）.docVIP

肿瘤标志物检测与临床（Detection and clinical study of tumor markers） Detection and clinical study of tumor markers Release time is 03 years, 03 months, 28, 10:54 In the study and clinical practice of cancer, early detection, early diagnosis and early treatment are the key. Tumor markers (Tumor, Marker, TM) have great practical value in tumor screening, diagnosis, prognosis and prognosis, evaluation of therapeutic efficacy and follow-up observation of high-risk groups. Since 80s, with the application of B lymphocyte hybridoma monoclonal tumor preparation technology matures, the large number of monoclonal antibodies against tumor, and at the same time immunological detection technology and the change rapidly (RIA, IRMA, ELISA, CLIA, IFA, TRFIA etc.) combined with the development of a large number of tumor markers the project is constantly in clinical application, has become one of the important indexes of tumor patients. 1, overview 1.1 generally speaking, tumor markers mainly refer to the substances secreted or exfoliated by cancer cells into the body fluid or tissues, or the substances that are produced by the new biological reactions in the body and into the body fluids or tissues. Some of these substances do not exist in the normal human body, only in the embryo, and in some cases of tumor patients, the content is more than the normal body content. By measuring its presence or content, it can assist in the diagnosis of the tumor, analyze the course of the disease, guide the treatment, monitor the recurrence or metastasis, and determine the prognosis. This type of TM is called humoral TM. With the development of molecular biology, from the molecular level found abnormal gene structure or function change and has a certain biological function of the gene product expression and tumor development are closely related, so the determination of oncogenes and tumor suppressor genes and its products are also listed TM. Because these substances exist on the cell membrane or in cells, su