微流控技术可控制备功能材料研究.docVIP

微流控技术可控制备功能材料研究* 徐建鸿，兰文杰，杜笛，骆广生 （清华大学化工系化学工程联合国家重点实验室，北京 100084） 摘要：近年来，微流控技术制备单分散功能材料成为了热点研究方向之一。本论文通过控制同轴微流控设备内多相流型进行了功能微米材料可控制备的研究，通过调节实验条件获得了尺寸和结构可控的液滴，双乳液和多层层流，结合溶剂萃取，溶剂挥发，原位交联和紫外聚合等快速固化方法成功制备得到了单分散PMMA，壳聚糖，聚苯乙烯微球，有机无机复合微球以及聚砜中空纤维管等功能材料。研究结果对微流控技术在功能材料制备中的应用提供了基础。 关键词：多相流；微流控；功能材料 中图分类号：TQ 028.8 文献标识码：A Controllable preparation of microscale materials in microfluidic devices XU Jianhong1，LAN Wenjie，DU Di，LUO Guangsheng (1Department, College, province, city postcode, China; 2Department, College, province, city postcode, China;) Abstract：The controlled preparation of microscale functional materials in microfluidic devices has been the focus of numerous studies in the last few years. In this work, we focus on the preparation of monodispersed microscale materials by controlling multi-phase flow in co-axial microfluidic devices. Based on the droplet formation in microfluidic devices, experiments on the solidification of monodispersed droplets (double emulsions) were conducted. Different solification methods including solvent extraction, solvent evaporation, crosslinking and UV-polymerization were used to preparation monodispersed PMMA, chitosan and PSt microparticles. The size and structure of the microparticles can be controlled.Based on the tri-phase co-laminar flow, experiments on the preparation of uniform tubes were conducted. The results will be very helpful for the development of novel technology and equipments for the preparation of monodispersed microscale materials, such as functional microspheres, microcapsules, hollow fiber membranes, and so on. Key words：multi-phase flow; microfluidic;functional material 引 言 功能微米材料在聚合物化工、医药化工、催化和高效分离材料方面有着非常广泛的应用。而在这些领域的应用中，对于微米材料的尺寸，尺寸分布以及结构都有着严格的要求。在新型微流控技术发展的基础上，很多研究者进行了将微流控技术用于单分散微球和微胶囊制备的研究。研究者一般先利用微分散方法制得单分散乳液，然后采用不同的快速固化方法将乳液固化得到相应的单分散微球和微胶囊。研究结果表明，采用微通道分散技术可以得到尺寸可控、形貌可控、组成可控和粒度均一的各种微球和微胶囊[1-5]。而对于特种形貌和结构的功能微米材料的研究还比较少。 本论文通过控制微流控设备内的多相流型，同时结合原位快速固化方法，进行单分散PMMA，壳聚糖，聚苯乙烯微球，有机无机复合微球以及聚砜中空纤维管等功能材料的可控制备研究。