a new saponin from tea seed pomace (camellia oleifera abel) and its protective effect on pc12 cells一个新的从茶籽皂素果渣(茶花鉴定亚伯)及其对pc12细胞的保护作用.pdfVIP

Molecules 2012, 17, 11721-11728; doi:10.3390/molecules171011721 OPEN ACCESS molecules ISSN 1420-3049 /journal/molecules Article A New Saponin from Tea Seed Pomace (Camellia oleifera Abel) and Its Protective Effect on PC12 Cells Xin-Fu Zhang 1,2, Ying-Ying Han 1, Guan-Hu Bao 1, Tie-Jun Ling 1, Liang Zhang 1, Li-Ping Gao 3,* and Tao Xia 1,* 1 Key Laboratory of Tea Biochemistry Biotechnology, Ministry of Education and Ministry of Agriculture, Anhui Agricultural University, Hefei 230036, China; E-Mails: zxftea@163.com (X.-F.Z.); hanyyfood@163.com (Y.-Y.H.); baoguanhu@ (G.-H.B.); lingtj@ (T.-J.L.); zhli2091@ (L.Z.) 2 College of Horticulture, Qingdao Agricultural University, Qingdao 266109, China 3 School of Life Science, Anhui Agricultural University, Hefei 230036, China; E-Mail: gaolp62@126.com * Authors to whom correspondence should be addressed; E-Mails: gaolp62@126.com (L.-P.G.); xiatao62@126.com (T.X.); Tel.: +86-551-578-6003; Fax: +86-551-578-5729. Received: 31 August 2012; in revised form: 24 September 2012 / Accepted: 24 September 2012 / Published: 1 October 2012 Abstract: A new triterpenoid saponin, oleiferasaponin A , was isolated from tea seed 1 pomace (Camellia oleifera Abel). The structure of oleiferasaponin A1 was elucidated on the basis of chemical and physicochemical evidence and was found to be 22-O-cis-2- hexenoyl-A1-barrigenol 3-O-[β-D-galactopyranosyl(1→2)] [β-D-glucopyranosyl(1→2)