a new tissue resonator indenter device and reliability study一个新的组织谐振器硬度计压头装置和可靠性研究.pdfVIP

Sensors 2011, 11, 1212-1228; doi:10.3390/s110101212 OPEN ACCESS sensors ISSN 1424-8220 /journal/sensors Article A New Tissue Resonator Indenter Device and Reliability Study Ming Jia *, Jean W. Zu and Alireza Hariri Department of Mechanical Industrial Engineering, University of Toronto/5 King’s College Road, Toronto, ON M5S 3G8, Canada; E-Mails:zu@mie.utoronto.ca (J.W.Z.); hariri@mie.utoronto.ca (A.H.) * Author to whom correspondence should be addressed; E-Mail: m.jia@utoronto.ca; Tel.: +1-416-946-3709; Fax: +1-416-946-5988. Received: 29 November 2010; in revised form: 31 December 2010 / Accepted: 18 January 2011 / Published: 20 January 2011 Abstract: Knowledge of tissue mechanical properties is widely required by medical applications, such as disease diagnostics, surgery operation, simulation, planning, and training. A new portable device, called Tissue Resonator Indenter Device (TRID), has been developed for measurement of regional viscoelastic properties of soft tissues at the Bio-instrument and Biomechanics Lab of the University of Toronto. As a device for soft tissue properties in-vivo measurements, the reliability of TRID is crucial. This paper presents TRID’s working principle and the experimental study of TRID’s reliability with respect to inter-reliability, intra-reliability, and the indenter misalignment effect as well. Keywords: tissue mechanical properties; TRID; reliability; indenter misalignment 1. Introduction The measurement of soft tissue mechanical pro