增殖性红斑概述（A review of proliferative erythema）.docVIP

增殖性红斑概述（A review of proliferative erythema） A review of proliferative erythema Erythroplasia (erythroplasia of Queyrat) is a rare cancer early disease, which is characterized in glans or wrapping on the limitations of the moist and shiny red plaques, slow development, long time for the development of epithelial carcinoma. Proliferative erythema etiology The whole layer of epithelium often involved, boundaries with the surrounding normal part is obvious, its tissue like skin carcinoma in situ, histopathological features of the papilla between the epidermal cells hypertrophy, slender apophysis form, like the finger like downward until the dermis, but the basement membrane integrity, dermal vascular dilatation, lymphocytes and plasma cells there are many special ribbon infiltration, visible epithelial cells in the hyperplastic epithelium, hyperchromatic nuclei, or multinucleated giant cell tumor, and dyskeratosis cells are few. Symptoms of proliferative erythema Symptoms of proliferative erythema: Ulceration, pruritus, induration of penis 1. good hair on the glans or foreskin, can also be seen in the labia minora, lips and mucous membranes and skin junction. 2. infants who had no prepuce penis of the disease, the disease is not limited to the elderly, the penis lesions on the glans, wrapping appear red, shiny, slightly raised, the boundary is obvious, irregular spots, typical lesions with lacquer like appearance, often moist, bright or granular appearance, soft texture then, a velvetlike, can appear secretion crusts or shallow ulcer. 3. skin development is extremely slow, can spread to the skin mucous membrane lesions, if scleroma, verrucous lesions and ulcers can be considered invasive changes can occur like diffusion, ulcer formation and invasive squamous cell carcinoma, if the ulcer and papillary proliferation can evolve into prickle cell carcinoma, 10% cases in primary damage occurred at the invasive squamous cell carcinoma; squamous cell carcinoma of the penis if