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computing inbreeding coefficients in large populations计算近交系数庞大的人口
Original article
Computing inbreeding coefficients
in large populations
THE Meuwissen Z Luo
Institute of Animal Physiology and Genetics Research,
Edinburgh Research Station, Roslin EH25 9PS, UK
(Received 21 October 1991; accepted 15 April 1992)
Summary - An algorithm for computing inbreeding coefficients in large populations is
presented. It is especially useful in large populations because of the small size of the
memory required, which is linear with population size, and its speed, if the number of
generations involved is not too large, ie not larger than about 12. The method is compared
with 2 other methods for computational speed and memory requirement. The presented
algorithm is suited for situations where the inbreeding coefficients for a few new animals
are to be computed given that their ancestor’s inbreeding coefficients were calculated
previously.
inbreeding coefficient / algorithm
Résumé - Le calcul des coefficients de consanguinité dans de grandes populations.
On présente un algorithme de calcul des coefficients de consanguinité pour de grandes
populations. Il est particulièrement adapté à ces populations à cause du faible volume de
mémoire d’ordinateur requis (il dépend linéairement de la taille de la population) et de la
rapidité de calcul quand le nombre de générations impliquées n’est pas trop élevé (c’est-
à-dire inférieur à environ 12). La méthode est comparée à2 autres méthodes du point de
vue de la vitesse de calcul et de la mémoire requise. Le présent algorithme est également
adapté aux situations de mise à jour où les coefficients de consanguinité correspondant
à un faible nombre d’animaux nouveaux doit être calculé en tirant parti des coefficients
calculés les anciens animaux.
pour
c
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