多肿瘤标志物蛋白芯片检测系统在临床应用中的评价（Evaluation of multiple tumor markers protein chip detection system in clinical application）.docVIP

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多肿瘤标志物蛋白芯片检测系统在临床应用中的评价（Evaluation of multiple tumor markers protein chip detection system in clinical application）.doc

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多肿瘤标志物蛋白芯片检测系统在临床应用中的评价（Evaluation of multiple tumor markers protein chip detection system in clinical application）

多肿瘤标志物蛋白芯片检测系统在临床应用中的评价（Evaluation of multiple tumor markers protein chip detection system in clinical application） I carefully collated documents, documents from the network I only collect and sort out In case of error Please check it yourself! Evaluation of multiple tumor markers protein chip detection system in clinical application Li Xinhe 1 Tannin 1 2, lift up 1 Wang Huimin 1 Liu Yanhong 1 Xia Hongyin 1 Zou Xiong, 1 Ming 2 1. 、 Central Laboratory of Qilu Hospital, Shandong University Jinan Two hundred and fifty thousand and twelve 2. 、 Department of Hematology, Qilu Hospital, Shandong University Jinan Two hundred and fifty thousand and twelve [Abstract] Objective: To evaluate the use of multiple tumor marker protein microarrays in healthy population screening, early diagnosis and prognosis monitoring Methods: HD-2OO1A multiple tumor marker protein chip assay system (C-12) was used to detect and analyze 8330 patients with malignant tumors There were 12 common tumor markers in serum of 9657 patients with benign diseases and 23531 healthy subjects (CA199 NSE CEA CA242 CA125 CA153 AFP FER F-PSA PSA Levels of beta -HCG and HGH) At the same time, 153 cases of negative specimens in the malignant tumor group were analyzed by E170 automatic immunoassay analyzer Results: the positive rate (85.6%) of the malignant tumor group was significantly higher than that of the benign disease group (41.2%) and the healthy examination group (7.03%) (P0.05) The specificity of C-12 in healthy population detection was 95% The detection rate of tumor in healthy population was 0.2% Conclusion: the technique of multiple tumor marker protein chip detection has high sensitivity and specificity The use of protein chip technology to detect multiple tumor markers can significantly improve the sensitivity of cancer diagnosis The utility model can be used for prognosis and curative effect observation It can also be used as an early screening method for asymptomatic people It has certain guiding s