a clinical decision support framework for incremental polyps classification in virtual colonoscopy临床决策支持在虚拟结肠镜息肉增量分类框架.pdfVIP

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a clinical decision support framework for incremental polyps classification in virtual colonoscopy临床决策支持在虚拟结肠镜息肉增量分类框架.pdf

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a clinical decision support framework for incremental polyps classification in virtual colonoscopy临床决策支持在虚拟结肠镜息肉增量分类框架

Algorithms 2010, 3, 1-20; doi:10.3390/a3010001 OPEN ACCESS algorithms ISSN 1999-4893 /journal/algorithms Article A Clinical Decision Support Framework for Incremental Polyps Classification in Virtual Colonoscopy Mariette Awad 1,*, Yuichi Motai 2, Janne Näppi 3 and Hiroyuki Yoshida 3 1 Electrical and Computer Engineering Department, American University of Beirut, PO Box 11- 0236, Riad El Solh, Beirut 1107 2020, Lebanon 2 School of Engineering, Virginia Commonwealth University, Richmond, VA, USA; E-Mail: ymotai@ (Y.M.) 3 Department of Radiology, Harvard Medical School and Massachusetts General Hospital, Boston, MA 02114, USA; E-Mail: jnappi@ (J.N.); yoshida.hiro@ (H.Y.) * Author to whom correspondence should be addressed; E-Mail: mariette.awad@.lb; Tel.: +011 961 3 31 22 96; Fax: +011 961 4 721 222. Received: 28 September 2009 / Accepted: 6 October 2009 / Published: 4 January 2010 Abstract: We present in this paper a novel dynamic learning method for classifying polyp candidate detections in Computed Tomographic Colonography (CTC) using an adaptation of the Least Square Support Vector Machine (LS-SVM). The proposed technique, called Weighted Proximal Support Vector Machines ( WP-SVM), extends the offline capabilities of the SVM scheme to address practical CTC applications. Incremental data are incorporated in the WP-SVM as a weighted vector space, and the only storage requirements are the hyper- plane parameters. WP-SVM performance evaluation based on 169 clinical CTC cases using