健胃愈疡颗粒对幽门螺杆菌阳性消化性溃疡患者的抗炎作用.PDFVIP

200 8 49 2 Jo urnal of T raditional Chinese M edicine, 2008, V ol . 49, No . 2 131 1 1 2 1 1 2 凌江红　黄李平　李家邦　潘宇政　黄耀全　申定珠 ( 1. 广西医科大学第一附属医院中医科, 广西壮族自治区南宁市双拥路6 号, 530021; 2 . 中南大学湘雅医院中西医结合研究所) ] ( Hp) ( P U ) 4 6 Hp P U , , HE ( - ) -2 B N F B Hp P U ( P 0. 01 P 0. 05) , NF -B , N F-B-2 ( P 0. 01 P 0. 05) N F -B , -2 , PU ] ; ; ; -2; B Anti-inflammation Effect of Jianwei Yuyang Granule on Helicobacter Pylori Positive PepticUlcer Patients 1 1 2 - , - , - , . L IN G J iang hong HU A N G L i ping LI Jia bang et al ( 1. T he First Af f iliated H osp ital of Guang x i M edical University , Nanning 530021; 2 . X iangy a H osp ital of Centre- outh Univer- sity) ABSTRA TObjectiveT o observ e the eff ect and mechanism o f Jianw ei Y uyang ( Str eng then t he stom ach to heal the ulcer ) Gr anule on peptic ulcer ( P U ) patients . MethodsT o tally 46 Hp -po sitive P U patients w ere r ando mized into trea tment gr o up ( t reated w ith J ianw ei Y uy ang Gr anule) and contr ol g ro up ( t reated w it h w est ern medicine ) . Befo re and after tr eatment , the infla m - matio n deg ree o f gastr ic antr um w as determ ined w ith HE staining a nd the expr ession of N F -B and -def ensin-2 in the gastr ic mu - co sa w as t est ed by im muno histochemistr y r espectiv ely . ResultsJianw ei Y uyang G ra nule signif icantly r elieved the chr onic infla m - matio n and activ e deg r ee of gastr ic antrum ( P 0. 01 and P 0 . 0