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2012年蛋白和抗体类药物销售额一览(List of protein and antibody drugs sales in 2012)
2012年蛋白和抗体类药物销售额一览(List of protein and antibody drugs sales in 2012)
AC]2012 protein and antibody drugs sales list of 7 people participated
1.TNF antibody
2012 sales: $26 billion 680 million; 2011 sales: $24 billion 40 million
Indication: rheumatoid arthritis
(1) adalimumab (adalimumab):Humira, TNF alpha monoclonal antibody, Abbott/Eisai, sales of $9 billion 534 million in 2012
(2) etanercept (etanercept),:Enbrel, TNF-, mAb, and Amgen/Pfizer/Takeda, with sales of $8 billion 406 million in 2012
(3) infliximab (infliximab),:Remicade, TNF- mAb, Centocor/Merck/Mitsubishi Tanabe, and 2012 sales of $7 billion 468 million
(4) golimumab (golimumab):Simponi, TNF alpha monoclonal antibody, Merck/Centocor/Mitsubishi Tanabe, 2012 sales of $654 million
(5) (certolizumab, pegol),:Cimzia, TNF, - mAb, UCB, Pharma, in 2012 sales of $613 million
2. cancer antibodies
2012 sales: $23 billion 740 million; 2011 sales: $21 billion 380 million
Indications: lymphoma, breast cancer, colorectal cancer, lung cancer, leukemia
(1) rituximab (rituximab),:Rituxan/MabThera, CD20- monoclonal antibodies, Genentech, non Hodgkins lymphoma, and 2012 sales of $7 billion 143 million
(2) trastuzumab (trastuzumab),:Herceptin, HER2- mAb, Genentech, HER2 positive breast cancer, 2012 sales of $6 billion 272 million
(3) bevacizumab (bevacizumab),:Avastin, VEGF- monoclonal antibodies, Genentech, colorectal cancer, and non-small cell lung cancer, with sales of $6 billion 139 million in 2012
(4) cetuximab (cetuximab),:Erbitux, EGFR- monoclonal antibodies, Eli, Lilly/Bristol-Myers, Squibb/Merck, Serono, colorectal cancer, and 2012 sales of $1 billion 874 million
(5) denosumab (denosumab):Xgeva, RANKL- mAb, Amgen/Daiichi Sankyo, bone cancer, sales of $748 million in 2012
(6) ipilimumab,:Yervoy, CD152- monoclonal antibodies, Bristol-Myers, Squibb, and multiple myeloma, with sales of $748 million in 2012
(7) panitumumab (panitumumab):Vectibix, EGFR- mAb, Takeda/Amgen, colorectal cancer, 2012 sales of $547 million
(8)
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