fto基因（fto基因）.docVIP

fto基因（fto基因） The FTO gene is an obesity related allele, also known as the obesity gene. People with FTO mutations in the body, if two copies vary, are 70% more likely to be obese than those who dont have variants. If only one copy of the FTO gene is mutated, the odds of obesity are 30% higher than those without a copy. Structure composition It was first identified by researchers at the University of Oxford, Mark Macarthy, and published in the April 2007 issue of the Journal science. (FTO, abbreviation for English Fat, Mass, and, Obesity, Associated). The allele called FTO. Certain genes in the human body usually appear in pairs, called alleles, localized on chromosome 16, one copy comes from the parent, and the other copies from the parent, showing a double helix structure. People with FTO mutations in the body, if two copies vary, are 70% more likely to be obese than those who dont have variants. gene If only one copy of the FTO gene is mutated, the odds of obesity are 30% higher than those without a copy. Minor variations are common in obese individuals. People with two copies of the variant weighed an average of three kilograms more than those with normal copies. Only 35% of whites in Europe carry two normal copies of the genome. Edit this paragraph Findings About 1 out of every 6 people in Europe carry about two variants of the FTO gene, according to the researchers. But they still dont know exactly how the FTO mutation contributes to obesity. Obesity is becoming a chronic disease all over the world because modern people are becoming less exercise and eating more and more. Medical research suggests that obesity increases the risk of type 2 diabetes, heart disease, cancer and other diseases. In the study of susceptibility genes of type II diabetes genome, Dr. Andrew T.Hattersley of the Peninsula Medical School in England found a FTO variant, this variant seems can improve BMI, increases the risk of diabetes. Further analysis of this variant in 38759 subjects conf