sipple综合征合并甲亢一例（A case of Sipple syndrome complicated with hyperthyroidism）.docVIP

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sipple综合征合并甲亢一例（A case of Sipple syndrome complicated with hyperthyroidism）.doc

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sipple综合征合并甲亢一例（A case of Sipple syndrome complicated with hyperthyroidism）

sipple综合征合并甲亢一例（A case of Sipple syndrome complicated with hyperthyroidism） A case of Sipple syndrome complicated with hyperthyroidism 2011-10-19 sun Bing, Guo Jizhen, Du Jian, Zhang Zubao, Yang Jian Sipple is a syndrome of multiple endocrine neoplasia (MEN, MEA) A, is a rare endocrine disease in our country, only 16 cases, the clinical manifestations of adrenal pheochromocytoma and medullary thyroid carcinoma or associated with hyperparathyroidism. Our hospital recently treated 1 cases of Sipple syndrome (combined hyperthyroidism) rare cases, is now in this case in the diagnosis, treatment and other aspects of discussion. Case report The patient, female, aged 45, was hospitalized with number 463211. As a result of increased blood pressure for 7 years, in June 18, 1997 the income of paroxysmal palpitation sweating for 2 years. The patients blood pressure was 160/101mmHg (1mmHg=0.133kPa) 7 years ago, and no symptoms were reported at the time. No treatment was done. 2 years ago appeared paroxysmal palpitations, Dohan, afraid of heat, accompanied by dry mouth, happy drink, nocturia 4~5 times, more volume, blood pressure continued at 150 to 160/101mmHg, nearly 20 months weight loss of nearly Jin jin. In the family history, the mother suffered from hypertension, emaciation and palpitation. The cause of the death was unknown, and there were no similar diseases among the other family members. After admission examination: blood pressure 130/90mmHg, heart rate 102 beats / min, emaciation, no exophthalmos, bilateral thyroid enlargement, of medium texture and smooth surface, and no abdominal vascular murmur, unexpected mass. Blood biochemical examination: normal total T3 and total T4 180nmol/L (normal value: 65 ~ 155nmol/L), free T3 (FT3) 32pmol/L (normal value 6 ~ 11.4pmol/L), free T4 (FT4) normal value 260pmol/L (32.2 + 6.4) pmol/L, thyroid stimulating hormone (s-TSH) and 0.15mU/L (normal value 0.3 ~ 5.0mU/L), thyroid peroxidase antibody (TPOAb) 16% (normal value 13%), thyr