宫颈环型电切术治疗宫颈上皮内瘤变疗效观察.docVIP

宫颈环型电切术治疗宫颈上皮内瘤变疗效观察【中图分类号】R713. 4【文献标识码】 B【文章编号】1672-3783(2010)07-0005-02 【摘要】目的 探讨宫颈环型电切术(loop electrosurgical excision procedure,LEEP)应用于宫颈上皮内瘤变(cervical intraepithelial neoplasia,CIN)的治疗效果。方法 2004年6月～2008年11月在我院宫颈疾病门诊诊断为CIN的部分患者采用LEEP进行治疗,术后随访至少2年。结果 术后6个月治愈率为98.29%,其中CINⅠ组治愈率为98.18%,CINⅡ～Ⅲ组治愈率为97.67%,两组比较差异无统计学意义(P0.05),术后1年复发率为1.82%。结论 采用LEEP治疗CIN安全、有效、创伤小、并发症少,术后需长期随访。 【关键词】宫颈上皮内瘤变;环型电切术;治愈率 Cervical ring type electrical treatment cervical intraepithelial neoplasia (sichuan area in sichuan AnAnShi chamber hospital 638000 chamber)(sichuan area in sichuan AnAnShi chamber hospital 638000 chamber) 【Abstract】 Objective to explore the cervix ring type of loop electrosurgical excision procedure (LEEP), applied to cerical intraepithelial neoplasia cervical intraepithelial neoplasia (CIN), the treatment effect. Methods in June 2004 ~ in November of 2008 in cervical disease outpatient CIN patients diagnosed using part of the LEEP treatment, patients were followed up for at least two years. Results the cure rate of 6 months, including 98.29% CIN group, CIN 98.18% cure rate ~ for 97.67% group, two groups of comparisons difference was statistically significant (P 0.05), and 1 year after 1.82% recurrence rate. Conclusion the LEEP CIN therapy is safe, effective, trauma, and postoperative complication to long-term follow-up. 【Keywords】#8239; Cerical Intraepithelial neoplasia Ring was cure 宫颈癌位居女性恶性肿瘤第二位,严重威胁妇女生命健康,如何在宫颈癌前病变期采取有效治疗措施阻止其发展,是预防宫颈癌的关键。近年来,宫颈环型电切术(loop electrosurgical excision procedure,LEEP)治疗宫颈上皮内瘤变(cervical intraepithelial neoplasia,CIN)在国内已有陆续报道。本文旨在探讨LEEP治疗方法及其疗效。 1 资料与方法 1.1 一般资料 对2004年6月～2008年11月在我院宫颈疾病门诊通过宫颈液基细胞学检查及阴道镜下活检方法诊断为CINⅠ～Ⅲ的部分病例采用LEEP治疗。CINⅠ56例,其中20例阴道镜检查不满意,36例伴有慢性宫颈炎(宫颈糜烂、宫颈赘生物等);CINⅡ～Ⅲ 33例,包括原位癌4例。患者年龄29～54岁,未生育者2例。 1.2 治疗方法 1.2.1 治疗时间 除绝经者外,均选择月经干净后2～7天。 1.2.2 治疗步骤 常规做好术前准备及相关辅助检查:血、尿常规,白带常规,凝血功能,心电图等。患者取膀胱截石位,常规消毒手术野,充分暴露宫颈管后,根据阴道镜图像,用卢戈液拟定手术范围及碘液标志移行区范围。用2%利多卡因5 ml宫颈3点、9点处注射行局部麻醉。接通电源及排烟管,将功率调为50～7