全容积三维超声心动图定量评价正常人、冠心病患者左心室收缩功.docVIP

全容积三维超声心动图定量评价正常人、冠心病患者左心室收缩功 　 作者：韩增辉，钱蕴秋，周晓东，张军，李军 【关键词】 左心室 【Abstract】 AIM: To validate the feasibility and accuracy of full volume three dimensional echocardiography （FV3DE） in evaluating the global and regional contractile function of left ventricle in normal persons and patients with coronary artery diseases. METHODS: FV3DE images were acquired in 16 normal subjects and 18 patients with coronary artery disease by a matrix array transducer, the global and regional volume and ejection fraction （EF） of left ventricle were measured by TomTec 4D LVanalysis software. At the same time, the results of global and regional volume and EF were compared with those measured by Simpsons method. RESULTS: The global volume and EF of left ventricle could be measured with FV3DE well and truly in the normal subjects and the patients. There were no statistically significant differences among the results of FV3DE and Simpsons method. Meanwhile, detailed data about regional volume and contractile function of left ventricle could be get by FV3DE. CONCLUSION: FV3DE is a novel, noninvasive technique capable of detecting global and regional volume and contractile function of left ventricle. 【Keywords】 echocardiography；threedimensional ultrasound；coronary artery disease；left ventricular function 【摘要】 目的：探讨新技术全容积三维超声心动图（FV3DE）定量检测正常人、冠心病患者左心室整体及各节段收缩功能的可行性与准确性. 方法：使用全容积三维超声成像技术，于心尖四腔切面采集16例正常人及18例冠心病患者左心室的“金字塔”三维数据库，使用容积及收缩功能分析软件，脱机测算左心室整体及各节段的容积及收缩功能，并与二维超声双平面Simpson法测量结果进行对比. 结果：无论在正常人及冠心病患者，FV3DE均可准确获得收缩末期和舒张末期的左心室容积、射血分数，与二维超声双平面Simpson法结果高度一致；另外，FV3DE数据脱机分析还可全面获得整个心动周期中左心室各壁各节段的局部容积及射血分数变化曲线. 结论：全容积三维超声心动图可以准确测量左心室容积，计算左心室整体收缩功能，并全面分析左心室各节段的收缩功能，为系统且无创的研究左心室功能开辟了新途径. 【关键词】 超声心动图；三维超声；冠心病；左心室功能 0引言 快速、安全而准确地测量左心室收缩功能在临床上有重要意义. 本研究我们应用新技术全容积三维超声心动图(full volume 3Dechocardiography, FV3DE)研究正常人及冠心病患者的左心室三维结构，使用脱机分析软件分别测量正常成人、冠心病患者的左心室整体及局部的心室容积及射血分数，以评价该技术测定左心室整体及局部节段收缩功能的可行性与准确性. 1对象和方法 1．1对象对照组：为健康志愿者16(男14，女2)例，年龄27～58（41.6±10.7）岁，经临床诊断及二维超声检查均为无心脏疾患者，血压正常，窦性心律，平均心率(75±8)次/min.