纳米银涂层尿管抗菌作用临床对比探究.docVIP

纳米银涂层尿管抗菌作用临床对比探究 　 作者：赵亚群，周敬安，刘广涛，郭红艳，王晓阳，赵莉，陈勤 【关键词】 纳米银涂层尿管；抗菌作用；对比研究 　　Clinical contrast study of antibacterial action by urinary catheters coated with nanometersilver 　　【Abstract】 AIM: To study the antibacterial action of urinary catheters coated with nanometersilver. METHODS: Catheterized patients in neurosurgery department were randomly divided into 2 groups：ordinary urinary catheter group and urinary catheter coated with nanometersilver group. After the patients with catheterization time less than 7 d were rejected， all 30 patients were studied including 17 with urinary catheter coated with nanometersilver and 13 with ordinary urinary catheter. Urine routine and urine culture were done before and 7, 14, 21, 28 d after urethral catheterization. The end of urinary catheters was cultured after a urinary catheter was pulled out. RESULTS: The positive number of urinary leukocytes before and 7, 14, 21, 28 d after urethral catheterization was 1, 5, 6, 8, 9, respectively for ordinary urinary catheter group,but for urinary catheter coated with nanometersilver group it was 0, 1, 2, 4, 5, respectively (Plt;0.05). The positive number of urine culture before and 7, 14, 21, 28 d after urethral catheterization was 0, 3, 5, 7, 8, respectively for ordinary urinary catheter group, but for urinary catheter coated with nanometersilver group it was 0, 0, 1, 3, 4, respectively (Plt;0.05). The Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureaus, Streptococcus viridans and Proteus species were found in 3, 4, 3, 1, 2 cases respectively in urine culture for ordinaryurinary catheter group, but for urinary catheter coated with nanometersilver group those were found in 2, 1, 1, 1, 0 cases respectively. Those microorganisms were found in 8, 3, 4, 3, 2 cases respectively in urinary catheter culture for ordinary urinary catheter group, but for urinary catheter coated with nanometersilver group, they were found in 3, 1, 2, 0, 1 cases respectively (Plt;0.05). CONCLUSION: Cathete