原创力文档a process for analysis of microarray comparative genomics hybridisation studies for bacterial genomes微阵列比较基因组杂交的过程分析研究细菌基因组.pdfVIP
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a process for analysis of microarray comparative genomics hybridisation studies for bacterial genomes微阵列比较基因组杂交的过程分析研究细菌基因组
BMC Genomics BioMed Central
Methodology article Open Access
A process for analysis of microarray comparative genomics
hybridisation studies for bacterial genomes
1,2 1 1 1
Ben Carter , Guanghui Wu , Martin J Woodward and Muna F Anjum*
Address: 1Department of Food and Environmental Safety, Veterinary Laboratories Agency-Weybridge, New Haw, Addlestone, Surrey KT15 3NB,
UK and 2South East Wales Trials Unit, Dept. Primary Care and Public Health, School of Medicine, Heath Park, Cardiff University, CF14 4XN, UK
Email: Ben Carter - b.carter@.uk; Guanghui Wu - g.wu@.uk;
Martin J Woodward - m.j.woodward@.uk; Muna F Anjum* - m.anjum@.uk
* Corresponding author
Published: 29 January 2008 Received: 6 March 2007
Accepted: 29 January 2008
BMC Genomics 2008, 9:53 doi:10.1186/1471-2164-9-53
This article is available from: /1471-2164/9/53
© 2008 Carter et al; licensee BioMed Central Ltd.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0),
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Background: Microarray based comparative genomic hybridisation (CGH) experiments have
been used to study numerous biological problems including understanding genome plasticity in
pathogenic bacteria. Typically such experiments produce large dat
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