a search engine to identify pathway genes from expression data on multiple organisms搜索引擎识别途径基因表达数据在多个生物.pdfVIP

BMC Systems Biology BioMed Central Methodology article Open Access A search engine to identify pathway genes from expression data on multiple organisms †1 †1 1 Chunnuan Chen , Matthew T Weirauch , Corey C Powell , 2 1 Alexander C Zambon and Joshua M Stuart* Address: 1Department of Biomolecular Engineering, University of California, Santa Cruz, California, 95064, USA and 2Department of Medicine, Gladstone Institute of Cardiovascular Disease, San Francisco, California 94158, USA Email: Chunnuan Chen - cchen@; Matthew T Weirauch - weirauch@; Corey C Powell - cpowell@; Alexander C Zambon - azambon@; Joshua M Stuart* - jstuart@ * Corresponding author †Equal contributors Published: 4 May 2007 Received: 18 January 2007 Accepted: 4 May 2007 BMC Systems Biology 2007, 1:20 doi:10.1186/1752-0509-1-20 This article is available from: /1752-0509/1/20 © 2007 Chen et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: The completion of several genome projects showed that most genes have not yet been characterized, especially in multicellular organisms. Although most genes hav