原创力文档a simple method for estimating genetic diversity in large populations from finite sample sizes一个简单的方法估算遗传多样性大量人口从有限的样本大小.pdfVIP
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a simple method for estimating genetic diversity in large populations from finite sample sizes一个简单的方法估算遗传多样性大量人口从有限的样本大小
BMC Genetics BioMed Central
Research article Open Access
A simple method for estimating genetic diversity in large
populations from finite sample sizes
Stanislav Bashalkhanov, Madhav Pandey and Om P Rajora*
Address: Canada Research Chair in Forest and Conservation Genomics and Biotechnology, Canadian Genomics and Conservation Genetics
Institute, University of New Brunswick, Faculty of Forestry and Environmental Management, 28 Dineen Drive, Fredericton, NB, E3B 6C2, Canada
Email: Stanislav Bashalkhanov - stanislav.bashalkhanov@unb.ca; Madhav Pandey - mpandey@unb.ca; Om P Rajora* - om.rajora@unb.ca
* Corresponding author
Published: 16 December 2009 Received: 6 April 2009
Accepted: 16 December 2009
BMC Genetics 2009, 10:84 doi:10.1186/1471-2156-10-84
This article is available from: /1471-2156/10/84
© 2009 Bashalkhanov et al; licensee BioMed Central Ltd.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0),
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Background: Sample size is one of the critical factors affecting the accuracy of the estimation of
population genetic diversity parameters. Small sample sizes often lead to significant errors in
determining the allelic richness, which is one of the most important and commonly used estimators
of genetic diversity in populations. Correct estimation of allelic richness in natural populati
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