a simple method to combine multiple molecular biomarkers for dichotomous diagnostic classification一个简单的方法为二分结合多个分子生物标志物的诊断分类.pdfVIP
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a simple method to combine multiple molecular biomarkers for dichotomous diagnostic classification一个简单的方法为二分结合多个分子生物标志物的诊断分类
BMC Bioinformatics BioMed Central
Methodology article Open Access
A simple method to combine multiple molecular biomarkers for
dichotomous diagnostic classification
†1 1,2 1
Manju R Mamtani , Tushar P Thakre* , Mrunal Y Kalkonde ,
1 1 1
Manik A Amin , Yogeshwar V Kalkonde , Amit P Amin and
Hemant Kulkarni†1
Address: 1Lata Medical Research Foundation, Nagpur, India and 2University of North Texas Health Science Center, Fort Worth, Texas, USA
Email: Manju R Mamtani - mamtani@; Tushar P Thakre* - tthakre@; Mrunal Y Kalkonde - mkalkonde@;
Manik A Amin - saiamin2004@; Yogeshwar V Kalkonde - yvkalkonde@; Amit P Amin - amit_p_amin@;
Hemant Kulkarni - hemant_kulkarnius@
* Corresponding author †Equal contributors
Published: 10 October 2006 Received: 13 May 2006
Accepted: 10 October 2006
BMC Bioinformatics 2006, 7:442 doi:10.1186/1471-2105-7-442
This article is available from: /1471-2105/7/442
© 2006 Mamtani et al; licensee BioMed Central Ltd.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0),
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Background: In spite of the recognized diagnostic potential of biomarkers, the quest for
squelching noise and w
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