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a survey of green plant trna 3-end processing enzyme trnase zs, homologs of the candidate prostate cancer susceptibility protein elac2绿色植物的调查trna 3 端处理酶trnase z,前列腺癌易感性蛋白质elac2同系物的候选人.pdfVIP

a survey of green plant trna 3-end processing enzyme trnase zs, homologs of the candidate prostate cancer susceptibility protein elac2绿色植物的调查trna 3 端处理酶trnase z,前列腺癌易感性蛋白质elac2同系物的候选人.pdf

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a survey of green plant trna 3-end processing enzyme trnase zs, homologs of the candidate prostate cancer susceptibility protein elac2绿色植物的调查trna 3 端处理酶trnase z,前列腺癌易感性蛋白质elac2同系物的候选人

Fan et al. BMC Evolutionary Biology 2011, 11:219 /1471-2148/11/219 RESEARCH ARTICLE Open Access A survey of green plant tRNA 3’-end processing enzyme tRNase Zs, homologs of the candidate prostate cancer susceptibility protein ELAC2 Lijuan Fan1,2,3, Zhikang Wang1,2,3, Jinyu Liu1,2,3, Weili Guo1,2,3, Jie Yan4 and Ying Huang1,2,3* Abstract Background: tRNase Z removes the 3’-trailer sequences from precursor tRNAs, which is an essential step preceding the addition of the CCA sequence. tRNase Z exists in the short (tRNase ZS L ) and long (tRNase Z ) forms. Based on the sequence characteristics, they can be divided into two major types: bacterial-type tRNase ZS and eukaryotic- type tRNase ZL S , and one minor type, Thermotoga maritima (TM)-type tRNase Z . The number of tRNase Zs is highly variable, with the largest number being identified experimentally in the flowering plant Arabidopsis thaliana. It is unknown whether multiple tRNase Zs found in A. thaliana is common to the plant kingdom. Also unknown is the extent of sequence and structural conservation among tRNase Zs from the plant kingdom. Results: We report the identification and analysis of candidate tRNase Zs in 27 fully sequenced genomes of green plants, the great majority of which are flowering plants. It appears that green plants contain multiple distinct tRNase Zs predicted to reside in different subcellular compartments. Furthermore, while the bacterial-type tRNase ZS S s are present only in basal land plants and green algae, the TM-type tRNase Z s

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