a schistosoma japonicum chimeric protein with a novel adjuvant induced a polarized th1 immune response and protection against liver egg burdens一个日本血吸虫嵌合蛋白与一种新型佐剂诱导极化th1免疫反应,保护肝脏卵负担.pdfVIP

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a schistosoma japonicum chimeric protein with a novel adjuvant induced a polarized th1 immune response and protection against liver egg burdens一个日本血吸虫嵌合蛋白与一种新型佐剂诱导极化th1免疫反应,保护肝脏卵负担.pdf

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a schistosoma japonicum chimeric protein with a novel adjuvant induced a polarized th1 immune response and protection against liver egg burdens一个日本血吸虫嵌合蛋白与一种新型佐剂诱导极化th1免疫反应,保护肝脏卵负担

BMC Infectious Diseases BioMed Central Research article Open Access A Schistosoma japonicum chimeric protein with a novel adjuvant induced a polarized Th1 immune response and protection against liver egg burdens 1 2 1 1 1 Xindong Xu , Dongmei Zhang , Wei Sun , Qingfeng Zhang , Jingjing Zhang , 1 2 1,2 Xiangyang Xue , Luhui Shen and Weiqing Pan* Address: 1Institute for Infectious Diseases Vaccine Development, Tongji University School of Medicine, 1239 Siping Road, Shanghai 200092, PR China and 2Department of Pathogen Biology, Second Military Medical University, 800 Xiang Yin Road, Shanghai 200433, PR China Email: Xindong Xu - xuxd1981@; Dongmei Zhang - dm_zhangcn@; Wei Sun - wayofsun1@; Qingfeng Zhang - qinf_zhang@; Jingjing Zhang - yeats4389@126.com; Xiangyang Xue - wzxxy@; Luhui Shen - slh0220@; Weiqing Pan* - wqpan0912@ * Corresponding author Published: 6 May 2009 Received: 18 October 2008 Accepted: 6 May 2009 BMC Infectious Diseases 2009, 9:54 doi:10.1186/1471-2334-9-54 This article is available from: /1471-2334/9/54 © 2009 Xu et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: Schitosomiasis japonica is still a significant public