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a primary health-care intervention on pre- and postnatal risk factor behavior to prevent childhood allergy. the prevention of allergy among children in trondheim (pact) study初级卫生保健干预前和产后的风险因素的行为以防止儿童过敏。
Storrø et al. BMC Public Health 2010, 10:443
/1471-2458/10/443
RESEARCH ARTICLE Open Access
A primary health-care intervention on pre- and
postnatal risk factor behavior to prevent
childhood allergy. The Prevention of Allergy
among Children in Trondheim (PACT) study
*
Ola Storrø , Torbjørn Øien, Christian K Dotterud, Jon A Jenssen, Roar Johnsen
Abstract
Background: This study aimed to evaluate the impact of a primary prevention intervention program on risk
behavior for allergic diseases among children up to 2 years of age. The setting was in ordinary pre- and postnatal
primary health care in Trondheim, Norway.
Methods: The Prevention of Allergy among Children in Trondheim, Norway (PACT) study invited all pregnant
women and parents to children up to 2 years of age in the community to participate in a non-randomized,
controlled, multiple life-style intervention study. Interventional topics was increased dietary intake of cod liver oil
and oily fish for women during pregnancy and for infants during the first 2 years of life, reduced parental smoking
and reduced indoor dampness. A control cohort was established prior to the intervention cohort with “follow up
as usual”. Questionnaires were completed in pregnancy, 6 weeks after birth and at 1 and 2 years of age. Trends in
exposure and behavior are described.
Results: Intake of oily fish and cod liver oil increased statistically significantly among women and infants in the
intervention cohort compared to the control cohort. There was a low postnatal smoking prevalence in both
cohorts, with a trend towards a decreasing smoking prevalence in the control cohort. There was no change in
indoor dampness or in behavior related to non- intervened life-style factors.
Conclusions: The dietary intervention seemed to be successful. The observed reduced smoking behavior
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