a novel approach in the treatment of neuroendocrine gastrointestinal tumors additive antiproliferative effects of interferon-γ and meta-iodobenzylguanidine一个新颖的方法治疗胃肠道神经内分泌肿瘤添加剂interferon-γ和meta-iodobenzylguanidine抗增殖的影响.pdfVIP
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a novel approach in the treatment of neuroendocrine gastrointestinal tumors additive antiproliferative effects of interferon-γ and meta-iodobenzylguanidine一个新颖的方法治疗胃肠道神经内分泌肿瘤添加剂interferon-γ和meta-iodobenzylguanidine抗增殖的影响
BMC Cancer BioMed Central
Research article Open Access
A novel approach in the treatment of neuroendocrine
gastrointestinal tumors: Additive antiproliferative effects of
interferon-γ and meta-iodobenzylguanidine
1 1 1
Michael Höpfner , Andreas P Sutter , Alexander Huether , Gudrun Ahnert-
2 1
Hilger and Hans Scherübl*
Address: 1Charité – Universitätsmedizin Berlin, Campus Benjamin Franklin, Medical Clinic I, Hindenburgdamm 30, 12200 Berlin, Germany and
2Charité – Universitätsmedizin Berlin, Campus Mitte, Institut für Anatomie, Philippstrasse 12, 10115 Berlin, Germany
Email: Michael Höpfner - michael.hoepfner@charite.de; Andreas P Sutter - andreas.sutter@charite.de;
Alexander Huether - alexander.huether@charite.de; Gudrun Ahnert-Hilger - gudrun.ahnert@charite.de;
Hans Scherübl* - hans.scherubl@charite.de
* Corresponding author
Published: 21 May 2004 Received: 22 December 2003
Accepted: 21 May 2004
BMC Cancer 2004, 4:23
This article is available from: /1471-2407/4/23
© 2004 Höpfner et al; licensee BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all
media for any purpose, provided this notice is preserved along with the articles original URL.
Abstract
Background: Therapeutic options to effectively inhibit growth and spread of neuroendocrine
gastrointestinal tumors are still limited. As both meta-iodobenzylguanidine (MIBG) and inter
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