原创力文档a procedure for the detection of linkage with high density snp arrays in a large pedigree with colorectal cancer检测过程的联系与高密度snp数组大谱系与结肠直肠癌.pdfVIP
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a procedure for the detection of linkage with high density snp arrays in a large pedigree with colorectal cancer检测过程的联系与高密度snp数组大谱系与结肠直肠癌
BMC Cancer BioMed Central
Research article Open Access
A procedure for the detection of linkage with high density SNP
arrays in a large pedigree with colorectal cancer
1 2 3
Anneke Middeldorp , Shantie Jagmohan-Changur , Quinta Helmer ,
4 4 5 2
Heleen M van der Klift , Carli MJ Tops , Hans FA Vasen , Peter Devilee ,
1 3 2,4
Hans Morreau , Jeanine J Houwing-Duistermaat , Juul T Wijnen and
Tom van Wezel* 1
Address: 1Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands, 2Department of Human Genetics, Leiden
University Medical Center, Leiden, The Netherlands, 3Department of Medical Statistics and Bioinformatics, Leiden University Medical Center,
Leiden, The Netherlands, 4Department of Clinical Genetics, Leiden University Medical Center, Leiden, The Netherlands and 5The Netherlands
Foundation for the Detection of Hereditary Tumours, Leiden, The Netherlands
Email: Anneke Middeldorp - j.w.middeldorp@lumc.nl; Shantie Jagmohan-Changur - s.c.jagmohan@lumc.nl;
Quinta Helmer - q.helmer@lumc.nl; Heleen M van der Klift - h.m.van_der_klift@lumc.nl; Carli MJ Tops - c.m.j.tops@lumc.nl;
Hans FA Vasen - hfavasen@stoet.nl; Peter Devilee - p.devilee@lumc.nl; Hans Morreau - j.morreau@lumc.nl; Jeanine J Houwing-
Duistermaat - j.j.houwing@lumc.nl; Juul T Wijnen - j.wij
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