原创力文档a survey of primary care physician practices in antibiotic prescribing for the treatment of uncomplicated male gonoccocal urethritis初级保健医生的调查实践抗生素处方治疗简单的男性gonoccocal尿道炎.pdfVIP
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a survey of primary care physician practices in antibiotic prescribing for the treatment of uncomplicated male gonoccocal urethritis初级保健医生的调查实践抗生素处方治疗简单的男性gonoccocal尿道炎
Falchi et al. BMC Family Practice 2011, 12:35
/1471-2296/12/35
RESEARCH ARTICLE Open Access
A survey of primary care physician practices
in antibiotic prescribing for the treatment of
uncomplicated male gonoccocal urethritis
1,2* 1,2 3 1,2 4 5
Alessandra Falchi , Andrea Lasserre , Anne Gallay , Thierry Blanchon , Patrice Sednaoui , François Lassau ,
Veronique Massari 1,2, Clément Turbelin1,2 and Thomas Hanslik1,6,7
Abstract
Background: The development of resistance to antimicrobial therapy by Neisseria gonorrhoeae causes on-going
problems for individual case management of gonorrhoea. Surveillance data about N. gonorrhoeae have indicated
an increase in the incidence of gonorrhoea in France in 2006. As a consequence of the development of antibiotic
resistance in N. gonorrhoeae, French guidelines excluded fluoroquinolones as a standard treatment for N.
gonorrhoeae. Ceftriaxone became the recommended treatment, associated with azithromycin for Clamydia
trachomatis infection. Our aim was to describe the practice patterns of general practitioners (GPs) in managing the
antibiotic treatment of patients with symptoms suggestive of uncomplicated male urethritis.
Methods: We developed a clinical vignette describing a man with typical gonococcal urethritis symptoms to elicit
questions about antibiotic treatment. We mailed the electronic questionnaire to a random sample of 1000 French
GPs belonging to the Sentinelles Network.
Results: By the end of the survey period, 350 vignettes were received, yielding a response rate of 35%. Sixty-six
GPs (20.2%) prescribed the recommended antibiotics for the simultaneous treatment of N. gonorrhoeae and C.
trachomatis infections, while 132 GPs (40.4
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