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a transcriptome anatomy of human colorectal cancers一个人类结肠直肠癌的转录组解剖学.pdf

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a transcriptome anatomy of human colorectal cancers一个人类结肠直肠癌的转录组解剖学

BMC Cancer BioMed Central Research article Open Access A transcriptome anatomy of human colorectal cancers 1 1 1 2 1 Bingjian Lü , Jing Xu , Maode Lai* , Hao Zhang and Jian Chen Address: 1Department of Pathology Pathophysiology, School of Medicine, Zhejiang University, PR , 310031, China and 2Department of Computer Science, School of Computer Science Technology, Zhejiang University, PR, 310023, China Email: Bingjian Lü - lbjsrrsh@; Jing Xu - x_j_1998@126.com; Maode Lai * - lmd@; Hao Zhang - wowzh@163.com; Jian Chen - jc@ * Corresponding author Published: 23 February 2006 Received: 12 August 2005 Accepted: 23 February 2006 BMC Cancer 2006, 6:40 doi:10.1186/1471-2407-6-40 This article is available from: /1471-2407/6/40 © 2006 Lü et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: Accumulating databases in human genome research have enabled integrated genome-wide study on complicated diseases such as cancers. A practical approach is to mine a global transcriptome profile of disease from public database. New concepts of these diseases might emerge by landscaping this profile. Methods: In th