a software framework for microarray and gene expression object model (mage-om) array design annotation基因表达微阵列的软件框架和对象模型(mage-om)阵列设计注释.pdfVIP

BMC Genomics BioMed Central Software Open Access A software framework for microarray and gene expression object model (MAGE-OM) array design annotation Matloob Qureshi and Alasdair Ivens* Address: Wellcome Trust Sanger Institute, Hinxton, Cambridgeshire, CB10 1SA, UK Email: Matloob Qureshi - matloob@; Alasdair Ivens* - alicat@sanger.ac.uk * Corresponding author Published: 20 March 2008 Received: 3 September 2007 Accepted: 20 March 2008 BMC Genomics 2008, 9:133 doi:10.1186/1471-2164-9-133 This article is available from: /1471-2164/9/133 © 2008 Qureshi and Ivens; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: The MIAME and MAGE-OM standards defined by the MGED society provide a specification and implementation of a software infrastructure to facilitate the submission and sharing of data from microarray studies via public repositories. However, although the MAGE object model is flexible enough to support different annotation strategies, the annotation of array descriptions can be complex. Results: We have developed a graphical Java-based application (Adamant) to assist with submission of Microarray designs to public repositories. Output of the application is fully compliant