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a user-friendly web portal for t-coffee on supercomputers一个用户友好的门户网站t-coffee超级计算机
Rius et al. BMC Bioinformatics 2011, 12:150
/1471-2105/12/150
SOFTWARE Open Access
A user-friendly web portal for T-Coffee on
supercomputers
1* 1 1 2 2 3
Josep Rius , Fernando Cores , Francesc Solsona , Jano I van Hemert , Jos Koetsier and Cedric Notredame
Abstract
Background: Parallel T-Coffee (PTC) was the first parallel implementation of the T-Coffee multiple sequence
alignment tool. It is based on MPI and RMA mechanisms. Its purpose is to reduce the execution time of the
large-scale sequence alignments. It can be run on distributed memory clusters allowing users to align data sets
consisting of hundreds of proteins within a reasonable time. However, most of the potential users of this tool are
not familiar with the use of grids or supercomputers.
Results: In this paper we show how PTC can be easily deployed and controlled on a super computer architecture
using a web portal developed using Rapid. Rapid is a tool for efficiently generating standardized portlets for a
wide range of applications and the approach described here is generic enough to be applied to other applications,
or to deploy PTC on different HPC environments.
Conclusions: The PTC portal allows users to upload a large number of sequences to be aligned by the parallel
version of TC that cannot be aligned by a single machine due to memory and execution time constraints. The
web portal provides a user-friendly solution.
Background based on terminals used over several decades. We
Nowadays, researchers in the field of genomics increas- address this issue by introducing a user-friendly portal
ingly require
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