原创力文档addition of a sequence from α2-antiplasmin transforms human serum albumin into a blood clot component that speeds clot lysis添加一个序列从人类血清白蛋白α2-antiplasmin转换成血块溶解血凝块组件,速度.pdfVIP
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addition of a sequence from α2-antiplasmin transforms human serum albumin into a blood clot component that speeds clot lysis添加一个序列从人类血清白蛋白α2-antiplasmin转换成血块溶解血凝块组件,速度
BMC Biotechnology BioMed Central
Research article Open Access
Addition of a sequence from α -antiplasmin transforms human
2
serum albumin into a blood clot component that speeds clot lysis
1,2 1 1
William P Sheffield* , Louise J Eltringham-Smith , Sharon Gataiance and
Varsha Bhakta2
Address: 1Department of Pathology and Molecular Medicine, McMaster University, 1200 Main Street West, Hamilton, Ontario, Canada and
2Research and Development, Canadian Blood Services, Hamilton, Ontario, Canada
Email: William P Sheffield* - sheffiel@mcmaster.ca; Louise J Eltringham-Smith - smithlo@mcmaster.ca;
Sharon Gataiance - gataian@mcmaster.ca; Varsha Bhakta - bhaktava@mcmaster.ca
* Corresponding author
Published: 3 March 2009 Received: 19 August 2008
Accepted: 3 March 2009
BMC Biotechnology 2009, 9:15 doi:10.1186/1472-6750-9-15
This article is available from: /1472-6750/9/15
© 2009 Sheffield et al; licensee BioMed Central Ltd.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0),
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Background: The plasma protein α -antiplasmin (αAP) is cross-linked to fibrin in blood clots by
2 2
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