原创力文档absolute count of t and b lymphocyte subsets is decreased in systemic sclerosist和b淋巴细胞绝对计数的子集是减少系统性硬化症.pdfVIP
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absolute count of t and b lymphocyte subsets is decreased in systemic sclerosist和b淋巴细胞绝对计数的子集是减少系统性硬化症
44 Eu Ro PE An J ouR nAl of MEd I CAl RE sEARC J anuary 29, 2010
Eur J Med Res (2010) 15: 44-46 © I. olzapfel Publishers 2010
ABsolutE Count of t And B lyMP oCytE suBsEts Is dECREAsEd
In systEMIC sClERosIs
t. Gambichler*, C. tigges*, B. Burkert, s. öxtermann, P. Altmeyer, A . Kreuter
department of dermatology, Ruhr-university Bochum, Bochum, Germany
Abstract munosuppressant-untreated ssc patients and healthy
Backg ound: Previous reports on lymphocyte subpop- controls.
ulations in systemic sclerosis (ssc) are conflicting.
therefore, we aimed to investigate the lymphocyte MAtERIAl And MEt ods
subsets in ssc patients who were not on immunosup-
pressive therapy. this was a prospective study on patients with ssc who
M ethods: lymphocyte subsets were assessed in the pe- were evaluated in the department of dermatology of
ripheral blood of ssc patients (n = 29) and healthy the Ruhr-university Bochum (Germany) from febru-
controls (n = 29) using the four colour flow cytometry ary 2007 to J uly 2008. ssc was diagnosed according to
method. Correlation studies were also performed in the classification system proposed by leRoy et al. [1] .
order to assess the relationship between lymphocyte We only included patients who had no history of
subsets and clinical parameters. photo pheres
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