abundance and functional diversity of riboswitches in microbial communities丰度和功能riboswitches在微生物群落的多样性.pdfVIP

BMC Genomics BioMed Central Research article Open Access Abundance and functional diversity of riboswitches in microbial communities 1 1 1,2 Marat D Kazanov* , Alexey G Vitreschak and Mikhail S Gelfand Address: 1Institute for Information Transmission Problems (the Kharkevich Institute) RAS, Bolshoi Karetnyi per. 19, Moscow, 127994, Russia and 2Faculty of Bioengineering and Bioinformatics, Moscow State University, Moscow 119992, Russia Email: Marat D Kazanov* - mkazanov@mail.ru; Alexey G Vitreschak - l_veter@mail.ru; Mikhail S Gelfand - gelfand@iitp.ru * Corresponding author Published: 1 October 2007 Received: 13 July 2007 Accepted: 1 October 2007 BMC Genomics 2007, 8:347 doi:10.1186/1471-2164-8-347 This article is available from: /1471-2164/8/347 © 2007 Kazanov et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: Several recently completed large-scale enviromental sequencing projects produced a large amount of genetic information about microbial communities (metagenomes) which is not biased towards cultured organisms. It is a good source for estimation of the abundance of genes and regulatory structures in both known and unknown members of microbia