原创力文档advances in hormone replacement therapy making the menopause manageable激素替代疗法的进步使更年期可控的.pdfVIP
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advances in hormone replacement therapy making the menopause manageable激素替代疗法的进步使更年期可控的
BMC Womens Health BioMed Central
Commentary Open Access
Advances in hormone replacement therapy: making the
menopause manageable
Santiago Palacios
Address: Palacios Institute of Womens Health, Calle Antonio Acuña, 9, 28009, Madrid, España
Email: Santiago Palacios - ipalacios@
Published: 27 November 2008 Received: 15 October 2008
Accepted: 27 November 2008
BMC Womens Health 2008, 8:22 doi:10.1186/1472-6874-8-22
This article is available from: /1472-6874/8/22
© 2008 Palacios; licensee BioMed Central Ltd.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0),
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
The importance of the results of some large, randomized controlled trials (RCTs) on Hormone
Replacement Therapy (HRT) has modified the risk/benefit perception of HRT. Recent literature
review supports a different management.
The differences in age at initiation and the duration of HRT are key points. HRT appears to
decrease coronary disease in younger women, near menopause; yet, in older women, HRT
increases risk of a coronary event. Although HRT is a recognized method in the prevention and
treatment of osteoporosis, it is not licensed for the prevention of osteoporosis as a first-line
treatment. The effectiveness
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